CBD Can Help With Depression


CBD has been shown to mitigate symptoms associated with depression by interacting with the endocannabinoid system, a specialized system found throughout your body. According to pre-clinical research, CBD plays a promising role in alleviating depression. About 25% of people in Europe suffer from anxiety or depression every year, the World Health Organisation reported. Antidepressants such as antipsychotic drugs and selective serotonin reuptake inhibitors help treat depression. However, recent clinical and scientific researches have identified CBD as a potential treatment for an array of conditions, including depression. Studies robustly support and even encourage the use of CBD as an antidepressant.


Depression is defined as feelings of anger, loss, and sadness that interfere with your day to day activities. Depression can affect individuals in different ways. The health condition may interfere with a person’s regular work and result in reduced productivity and lost time. Further, depression can influence some chronic health conditions and even relationships.

Depression can make certain conditions worse, including cardiovascular disease, arthritis, cancer, obesity, diabetes, and asthma. Feeling down sometimes is a regular part of life; however, feeling hopeless or miserable continually could mean that you are suffering from depression. It is important to note that depression is a serious health concern, and if not properly treated, it can get worse.

Depression can cause a plethora of symptoms and can affect children, women, and men uniquely. Men dealing with the condition may exhibit symptoms such as aggressiveness, anxiousness,  restlessness, irritability, and anger. Women may display symptoms such as decreased energy, greater fatigue, irritability, talking slowly, and thoughts of suicide. Children may show symptoms such as mood swings, intense sadness, digestive problems, loss of energy, and weight gain or loss.

There are many causes of depression, ranging from circumstantial to biological. Common causes of this condition include chronic pain, insomnia, family history, alcohol or drug abuse, and early childhood trauma.

CBD and Depression

CBD has been shown to play a significant role in treating this mental disorder. Your body synthesizes its own cannabinoids known as endocannabinoids with the help of fatty acids. Foods such as seeds, nuts, and fish are rich in omega-3 fatty acids.

Research shows that CBD can interact with your endocannabinoid system, a network of cell receptors that help govern sleep, appetite, mood, and other functions. Endocannabinoids attaches to specific receptors in your brain, exacerbating the action of the neurochemical serotonin responsible for alleviating stress and enhancing mood.

CBD boosts the activity of the receptors to which the neurochemical serotonin attaches, ameliorating the symptoms of depression. CBD induces the relaxing and calming effects by optimizing and releasing serotonin

THC has been found to be specifically effective for sudden flare-ups of the disorder because it releases dopamine in the brain. Mental state, stress, diet, and exercise can affect serotonin and dopamine. That’s why individuals suffering from anxiety and depression produce less of these two chemicals. A combination of THC and CBD can help people with acute sadness.


Scientific studies have demonstrated that CBD can play a therapeutic role in treating anxiety and depression.

A study published in the British Journal of Pharmacology found that CBD exhibited antidepressant effects that were comparable to a widely known antidepressant called imipramine. The researchers placed the mice through a swimming test to learn the effects of cannabidiol on motivation. They found that CBD enhanced the physical activity of animals. An animal model study conducted in 2016 found that cannabidiol was an effective antidepressant and mice treated with CBD showed increased motivation and activeness.

Another study found that the endocannabinoid system plays a crucial role in alleviating depression. The research concluded that a lack of endocannabinoid signaling produces a depressive-like phenotype and using CBD to reverse this deficiency can help treat depression-related symptoms.